Multiscale Modeling in Biomechanics and Mechanobiology by Suvranu De (English) P

Description: Multiscale Modeling in Biomechanics and Mechanobiology by Suvranu De, Wonmuk Hwang, Ellen Kuhl Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the readers understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models.Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines.Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology. Back Cover Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the readers understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology. " Author Biography Prof Suvranu De serves as Professor and Head of the Department of Mechanical, Aerospace and Nuclear Engineering (MANE) and Director of the Center for Modeling, Simulation and Imaging in Medicine (CeMSIM) at Rensselaer Polytechnic Institute, NY, USA. His research is at the intersection of computational mechanics and the health sciences. He currently serves on the editorial boards of the Journal of Computational Surgery, International Journal of Modern Mechanics, International Journal of Computational Methods, and Computers & Structures. Prof De has authored or co-authored 12 book chapters, 97 papers in peer-reviewed journals and more than 187 papers appearing in conference proceedings. He has co-edited a book on Computational Modeling in Biomechanics (Springer, 2010). He is also a member of various editorial boards, national and international technical committees and workgroups.Dr Wonmuk Hwang is an expert in computational biophysics. With a Ph.D. degree in theoretical condensed matter physics at Boston University, his research changed to biomolecular simulation during his postdoctoral training at Massachusetts Institute of Technology. His research focuses on mechanics and self-assembly of biofilaments and molecular motors. He has made a number of discoveries about their operation mechanisms. Dr Hwang is currently Associate Professor of Biomedical Engineering at Texas A&M University. He has over 45 publications in international refereed journals and is a developer of the molecular dynamics simulation program, CHARMM (Chemistry at Harvard Molecular Mechanics). Prof Ellen Kuhl is an Associate Professor of Mechanical Engineering, Bioengineering (affiliate), and Cardiothoracic Surgery (courtesy). Her area of professional expertise is Computational Biomechanics, the creation of theoretical and computational models to predict the acute and chronic response of living biologicaltissue to environmental changes during development and disease progression. Her specific interest is the multiscale modeling of growth and remodeling, the study of how biological tissues adapt their form and function to changes in mechanical loading, and how this adaptation could be traced back to structural alterations on the cellular or molecular levels. Growth and remodeling might be induced naturally, e.g., through elevated pressure, stress, or strain, or interventionally, e.g., through prostheses, stents, tissue grafts, or stem cell injection. Combining theories of electrophysiology, biophysics, and continuum mechanics, her lab has specialized in predicting the chronic loss of form and function in growing and remodeling cardiac tissue using patient-specific custom-designed finite element models. Table of Contents 1. Proteins: Ssp DnaE Intein.- 2. Protein Crystals: Molecular to Continuum Level Models based on Crystal Plasticity Theory.- 3. Molecular Motors: Cooperative Phenomena of Multiple Molecular Motors. – 4. Biofilament dynamics: Line-to-rod-level Descriptions.- 5. Primary Cilia: Multi-Scale Structures that integrate Biomechanics and Mechanobiology. – 6. Biological Scaffolding: Reduced-Order Network Models.- 7. Transport phenomena: Computational models for convective and diffusive transport in capillaries and tissue.- 8.Tendons and ligaments: Current state and future directions. – 9. Arteries: Mechanics, Mechanobiology, and the Need for a New Class of Models.- 10. Mitral Valves: A computational framework. – 11. Biological systems: Multiscale modeling based on Mixture Theory. Long Description Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the readers understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology. " Feature Outlines theoretical and computational models that link biological phenomena across multiple length and time scales Develops the readers understanding of multiscale phenomena in biomechanics and mechanobiology Introduces a mathematical framework and computational techniques for creating predictive multiscale models Details ISBN1447172299 Publisher Springer London Ltd Year 2016 ISBN-10 1447172299 ISBN-13 9781447172291 Format Paperback Imprint Springer London Ltd Place of Publication England Country of Publication United Kingdom Edited by Wonmuk Hwang DEWEY 570.285 Language English Media Book Pages 286 AU Release Date 2016-08-23 NZ Release Date 2016-08-23 UK Release Date 2016-08-23 Author Ellen Kuhl Edition Description Softcover reprint of the original 1st ed. 2015 Publication Date 2016-08-23 Alternative 9781447165989 Audience Professional & Vocational Illustrations 63 Illustrations, color; 21 Illustrations, black and white; VIII, 286 p. 84 illus., 63 illus. in color. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:99129998;

Price: 224.63 AUD

Location: Melbourne

End Time: 2025-02-07T23:59:18.000Z

Shipping Cost: 59.27 AUD