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Alzheimers Disease Research: What Has Guided Research So Far and Why It Is High

Description: Alzheimers Disease Research by Christian Behl Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description This book highlights the key phases and central findings of Alzheimers Disease research since the introduction of the label Alzheimers Disease in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimers drugs. As the reader is taken through the major developments in Alzheimers Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimers Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimers pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explainthe pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed?In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimers research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimers Disease research.The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimers Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimers research community is finally ready to shed its amyloid-straitjacket that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimers Disease research and provide a new and broader perspective on this age-dependent brain disease. Author Biography Christian Behl is Professor of Pathobiochemistry and Director of the Institute of Pathobiochemistry at the University Medical Center of the Johannes Gutenberg University Mainz, Germany. He has been closely following Alzheimers Disease research since the early 1990s, when he first got involved into the field himself during his time at the Salk Institute for Biological Studies, La Jolla, USA. He stayed active in the field all through his research station at the Max Planck Institute of Psychiatry, Munich, Germany, and later in Mainz. There his current research (in Mainz) focuses on the cellular degradation mechanism autophagy in the context of neurodegeneration and aging. For quite some time Behl has been an active advocate for widening the focus of Alzheimers Disease research to improve the understanding of this complex, age-related brain disorder. Behl is member of several scientific boards, including the German Alzheimer Foundation. Details ISBN 3031315693 ISBN-13 9783031315695 Title Alzheimers Disease Research Author Christian Behl Format Hardcover Year 2023 Pages 652 Edition 2023rd Publisher Springer International Publishing AG GE_Item_ID:161457107; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. 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End Time: 2025-01-27T07:24:37.000Z

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Alzheimers Disease Research: What Has Guided Research So Far and Why It Is High

Item Specifics

Restocking Fee: No

Return shipping will be paid by: Buyer

All returns accepted: Returns Accepted

Item must be returned within: 30 Days

Refund will be given as: Money Back

ISBN-13: 9783031315695

Book Title: Alzheimers Disease Research

Number of Pages: Xxv, 652 Pages

Language: English

Publication Name: Alzheimer's Disease Research : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift

Publisher: Springer International Publishing A&G

Publication Year: 2023

Subject: Neurology, Life Sciences / Neuroscience, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Internal Medicine

Type: Textbook

Item Weight: 47.6 Oz

Author: Christian Behl

Subject Area: Science, Medical

Item Length: 9.3 in

Item Width: 6.1 in

Format: Hardcover

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